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Chromatin architecture and epigenetic mechanisms in axon regeneration after injury and obesity

Field of Study:
Cell biology, Molecular biology, Epigenetics, Neuroscience
Department:
Neuroscience
Rank of Student:
Junior and Senior students who have already had previous lab experience and want to reach higher level of research independence and deeper expertise in more complex techniques.
Desired Majors:
Biology, Biochemistry, Molecular Genetics, Neuroscience
Hours per Week:
20
Compensation Type:
Academic Credit,
Salary / Stipend,
Work-Study,
Voluntary Experience
Application Deadline:
Contact:
Ilaria.palmisano@osumc.edu
Private
Public
Project Description
We are investigating different mechanisms (including chromatin 3D architecture, cellular energetic, transcription and epigenetic factors, and DNA damage) in the response of neuronal and non-neuronal cells to metabolic alterations driven by obesity and axonal injury.
We will perform molecular and cellular studies in mouse models of obesity, spinal cord and peripheral nerve injury. The student will be exposed to several lab techniques and trained with the expectation that they will eventually be able to conduct independent research.
Duties: mice handling and management; basic lab chores (management and organization of the lab, lab inventory, preparing stock solutions); assist lab personnel in experiments; perform independent experiments and data analysis; keep lab records; actively and critically participate in weekly lab meetings and journal clubs.
Additional Information
Only strongly committed applicants will be considered
Required Applicant Information
Cv and cover letter
Required or Desired Skills
MUST:
Strong commitment and enthusiasm
Interest in cell and molecular biology research
Interest in pursuing graduate program education
Tidiness and precision
Pipetting skills
Basic experience in mouse work
Basic experience in histology

PREFERRED:
Basic experience in molecular biology

Faculty Member Lead:
Ilaria Palmisano
Starting Semester:
Autumn,
Spring,
Summer
Length of Project (in semesters):
6