Field of Study:
Immunology and Epigenetics
Department:
Microbial Infection and Immunity
Rank of Student:
Freshman to Junior
Desired Majors:
Biomedical Science or bio-related
Hours per Week:
15
Compensation Type:
Academic Credit,
Work-Study,
Voluntary Experience
Application Deadline:
Contact:
Lio Lab (jerryliolab@gmail.com)
Private
Public
Project Description
Our lab studies how Vitamin C (VC) deficiency impacts the immune system. Recent studies have shown that VC is not just an antioxidant but also a cofactor for epigenetic enzymes, which are essential for gene regulation and cell differentiation. Our lab has discovered that VC is necessary for antibody responses by promoting DNA demethylation. Current projects include studying the role of VC deficiency in vivo using mouse models of infection and tumor. Other projects include understanding how DNA methylation is regulated in immune cells.
We also have projects involved in biological engineering. We have developed several novel flow cytometry techniques and also new method for immunotherapy.
We also have projects involved in biological engineering. We have developed several novel flow cytometry techniques and also new method for immunotherapy.
Required Applicant Information
Transcripts, CV, career goal, interest
Required or Desired Skills
Preferably has prior experience, including using a micropipette and aseptic techniques. Willing to work with mice, including dissection.
Faculty Member Lead:
Jerry Lio
Starting Semester:
Autumn,
Spring,
Summer
Length of Project (in semesters):
8