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The role of gut microbiota in immunology with a focus on rheumatoid arthritis

Field of Study:
Biology, Bochemistry, Molecular biology
Department:
Dept of Internal Medicine
Rank of Student:
Junior and Senior
Desired Majors:
Biology, Bochemistry, Molecular biology
Hours per Week:
20
Compensation Type:
Academic Credit,
Salary / Stipend,
Work-Study,
Voluntary Experience
Application Deadline:
Contact:
Email: joyce.wu2@osumc.edu
Private
Public
Project Description
Two undergraduate research positions are available for a motivated, enthusiastic and organized candidates to work on studying the role of gut microbiota in the development of autoimmune arthritis. The Wu lab has a strong focus on both systemic and mucosal immunology. We aim to understand the immunomodulation role of human pathobionts or mouse commensals in the development of gut-distal autoimmune diseases including autoimmune arthritis and lung pathology by using murine arthritis models and human patient samples.
Additional Information
Wu lab is looking for someone to work for AT LEAST two years; i.e. if you are a senior soon to graduate, you will work full time for two years after graduation. If you are a junior, you will work two semesters (20hrs/week)+ one year after graduate.
Required Applicant Information
Your CV, a transcript, and the cover letter (career goal and why you are applying this position).
Required or Desired Skills
Duties and Responsibilities:
Prior experience with handling mice is not necessary but he or she must be comfortable working with mice, as this work will primarily involve working with transgenic mouse models.
Maintaining mouse colony including PCR and qPCR genotyping, etc.
Tissue collection and microbial profiling by qPCR
Flow Cytometry analysis
Data analysis, data recording and organization
Hours: 20 hrs/week and a commitment of at least two years.
Faculty Member Lead:
Joyce Wu
Starting Semester:
Autumn,
Spring,
Summer
Length of Project (in semesters):
2