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Below is a list of open undergraduate research opportunities. Please be aware that these are not the only available positions for undergraduates to get involved in research at Ohio State. Typically, students seek their position out by following the "3 Steps to Getting Involved." The Office of Undergraduate Research & Creative Inquiry is here to help students through this process; please visit our homepage to schedule an advising appointment with a staff member! 

  
  
  
Project Description
Position Description
  
What rank of students are encouraged to apply?
What majors of students are encouraged to apply?
What are the approximate number of hours per week that the student is expected to be participating in the research?
Which semester would the student begin their work?
  
  
  
  
What information should applicants provide?
Is there any additional information that you would like to provide?
Project NameStiffness Matched and Resorbable Metals for Bone Fixation Devices
General Field of StudyBiomedical Device Design and Manufacturing and Regenerative Medicine
Faculty Member LeadDr. David Dean, Departments of Materials Science and Engineering/Plastic and Reconstructive Surgery, David.Dean@osumc.edu
Project Description
Current bone fixation devices are often overly stiff compared to bone mechanics and cause stress shielding of the bone that may result in osteolysis around the device and eventually fixation failure. Additionally, these fixation devices are generally made from overly stiff materials and are therefore at risk of failure due to stress shielding or stress concentrations. They are usually entirely non-resorbable and either require another surgery for removal or remain in the host indefinitely. To resolve these disadvantages, we are developing new strategies for metal fixation of bone that includes stiffness-matched metals that better facilitate bone healing without interrupting normal stress-strain trajectories and may also resorbable metals that can safely be metabolized in the body while allowing for natural bone healing processes to take over. These new materials require careful development for quality control in the manufacturing process so that any toxins introduced in manufacture are removed prior to exposure to cells and tissue. The goal of this work is to improve on current strategies for metal fixation design and processing to provide a material that is non-cytotoxic and therefore safe for implantation.
Position Description
Undergraduate research assistants will actively participate in experiment planning, protocol development, and data acquisition and analysis using scanning electron microscopy, biochemical assays (e.g., cytotoxicity studies), mechanical testing and any other techniques required to provide evidence of what is happening at the surface of the implant. Other responsibilities include inventory, clerical work, health and safety, lab cleaning and organization.
Please indicate any required or desired skills or qualifications that may be needed:Candidates must be reliable, must be a self‐directed learner and be able to work independently, must work well as part of a team, and is highly flexible in terms of the type of work they'll be doing.
What rank of students are encouraged to apply?
Candidates should be pursuing a technical undergraduate degree (engineering preferred) at The Ohio State University (freshman and sophomores preferred), have maintained a GPA (high school and/or college) greater than 3.0 is preferred, have strong math skills, strong communication skills, and have strong analytical and problem solving skills.
What majors of students are encouraged to apply?
MSE, BME, CBE, MAE, ISE, CSE, Premedical, Biology, Neuroscience, Chemistry.
What are the approximate number of hours per week that the student is expected to be participating in the research?
5-10 in fall and spring full time (38.5) in summer. During fall and spring candidates must be willing to work 5 hrs/week during the school work and able to work at least 2 consecutive hours on any work day.
Which semester would the student begin their work?
We are looking for volunteers to begin as soon as possible to begin training on necessary techniques.
Approximately how many semesters or months do you predict this research postion lastingIt is preferable that candidates commit to working in the lab throughout their undergraduate education for as long as they would like to pursue the research.
Will the student be working for academic credit, salary/stipend, work-study experience, or voluntary experience?We will consider all options interested candidates. Initially, students will obtain voluntary experience, but there are options for work-study, academic credit, and potentially a stipend if funding permits.
End Date11/30/2020
How/who should interested students contact?Qualified students should email the following to Dr. David Dean at David.Dean@osumc.edu (dean.1016)
What information should applicants provide?
(1) Your resume with the following:
(a) Name and contact information (home address, email address, and phone number)
(b) University Rank (e.g. sophomore) and anticipated graduation month and year (e.g., May 2024)
(c) Declared Major(s) and Minor(s)
(d) Relevant experiences (e.g., courses, previous research activities, previous work experience)
(2) A maximum 1 page letter of interest documenting:
(a) Why you are interested
(b) how you qualify for the position (e.g., relevant past experiences)
(c) current career goals if any
(d) Weekly Schedule of available times to attend lab meetings or work on research activities for Fall 2020
Is there any additional information that you would like to provide?
 
Project NameStem Cells for 3D Printed Resorbable Polymer Bone Tissue Engineered Implants
General Field of StudyTissue Engineering, Biofabrication, and Regenerative Medicine
Faculty Member LeadDr. David Dean, Departments of Materials Science and Engineering/Plastic and Reconstructive Surgery, David.Dean@osumc.edu
Project Description
This project will work to improve bone extracellular matrix deposition and osseointegration of a resorbable polymer, tissue engineered, implant to replace a large segmental bone defect. Current standard of care for critical-sized defects includes autografting, allografting and xenografting, all of which have several disadvantages in the clinic. In particular, we hope to create a 3D-printed resorbable implant that can act as a substitute during the healing process, will induce bone to regenerate in the area, and will resorb at a known time allowing for host tissue to remodel the area. 3D-printing allows for custom-design fabrication of implants to fit any required shape. The implants that are printed are then cultured with stem cells that can differentiate into osteoblasts and secrete mineralized bone-like extracellular matrix that will facilitate osteogenesis at the implant site. In this work, we expect that the undergraduate assistant will assist in experiment planning and to improve our cell culture regime for optimal bone substitute formation, and will carry out those experiments to validate optimized conditions.
Position Description
Undergraduate research assistants will actively participate in experiment planning, protocol development, and data acquisition and analysis using cell culture methods including basic cell culture, microscopy, biochemical assays, qPCR, histology, mechanical testing and any other techniques required to provide evidence of what is happening at the surface of the implant. Other responsibilities include inventory, clerical work, health and safety, lab cleaning and organization.
Please indicate any required or desired skills or qualifications that may be needed:Candidates must be reliable, must be a self‐directed learner and be able to work independently, must work well as part of a team, and is highly flexible in terms of the type of work they'll be doing.
What rank of students are encouraged to apply?
Candidates should be pursuing a technical undergraduate degree (engineering preferred) at The Ohio State University (freshman and sophomores preferred), have maintained a GPA (high school and/or college) greater than 3.0 is preferred, have strong math skills, strong communication skills, and have strong analytical and problem solving skills.
What majors of students are encouraged to apply?
MSE, BME, CBE, MAE, ISE, CSE, Premedical, Biology, Neuroscience, Chemistry.
What are the approximate number of hours per week that the student is expected to be participating in the research?
5-10 in fall and spring full time (38.5) in summer. During fall and spring candidates must be willing to work 5 hrs/week during the school work and able to work at least 2 consecutive hours on any work day.
Which semester would the student begin their work?
We are looking for volunteers to begin as soon as possible to begin training on necessary techniques.
Approximately how many semesters or months do you predict this research postion lastingIt is preferable that candidates commit to working in the lab throughout their undergraduate education for as long as they would like to pursue the research.
Will the student be working for academic credit, salary/stipend, work-study experience, or voluntary experience?We will consider all options interested candidates. Initially, students will obtain voluntary experience, but there are options for work-study, academic credit, and potentially a stipend if funding permits.
End Date11/30/2020
How/who should interested students contact?Qualified students should email the following to Dr. David Dean at David.Dean@osumc.edu (dean.1016)
What information should applicants provide?
(1) Your resume with the following:
(a) Name and contact information (home address, email address, and phone number)
(b) University Rank (e.g. sophomore) and anticipated graduation month and year (e.g., May 2024)
(c) Declared Major(s) and Minor(s)
(d) Relevant experiences (e.g., courses, previous research activities, previous work experience)
(2) A maximum 1 page letter of interest documenting:
(a) Why you are interested
(b) how you qualify for the position (e.g., relevant past experiences)
(c) current career goals if any
(d) Weekly Schedule of available times to attend lab meetings or work on research activities for Fall 2020
Is there any additional information that you would like to provide?
 
Project Namebiomolecular condensates
General Field of StudyRNA biology, Genetics and Bioinformatics
Faculty Member LeadWen Tang, Department of Biological Chemistry & Pharmacology
Project Description
We are interested in understanding the mechanisms involved in formation and function of non-coding RNAs. Working primarily on nematodes, our group is focused on studying the role of small RNAs in genome maintenance and epigenetic inheritance.
Position Description
The position is best suited for someone who loves laboratory research and wants to continue learning about biology.
Duties include: Assist lab personnel with research projects; Perform some independent research and analyze data; Participate in lab meeting and planning.
Please indicate any required or desired skills or qualifications that may be needed:1. Actively seeks opportunities to increase skills; 2. General experience in molecular biology (PCR, DNA and RNA isolation, cloning); 3. Able to use experience to perform a variety of new techniques;
What rank of students are encouraged to apply?
Sophomore or Junior students who plan to apply for graduate and medical schools
What majors of students are encouraged to apply?
Molecular Genetics, Biochemistry, and Biology
What are the approximate number of hours per week that the student is expected to be participating in the research?
10~20
Which semester would the student begin their work?
Fall, Spring, Summer
Approximately how many semesters or months do you predict this research postion lasting2-4 semesters
Will the student be working for academic credit, salary/stipend, work-study experience, or voluntary experience?Credits can be obtained through the Course 4998; Salary is possible
End Date12/31/2020
How/who should interested students contact?Wen Tang <wen.tang@osumc.edu>
What information should applicants provide?
CV with GPA and availability
Is there any additional information that you would like to provide?